[HTML][HTML] The effects of acutely administered 3, 4-methylenedioxymethamphetamine on spontaneous brain function in healthy volunteers measured with arterial spin …

RL Carhart-Harris, K Murphy, R Leech, D Erritzoe… - Biological …, 2015 - Elsevier
Abstract Background The compound 3, 4-methylenedioxymethamphetamine (MDMA) is a
potent monoamine releaser that produces an acute euphoria in most individuals. Methods In
a double-blind, placebo-controlled, balanced-order study, MDMA was orally administered to
25 physically and mentally healthy individuals. Arterial spin labeling and seed-based resting
state functional connectivity (RSFC) were used to produce spatial maps displaying changes
in cerebral blood flow (CBF) and RSFC after MDMA administration. Participants underwent …